The Parkinson’s Protocol™ By Jodi Knapp Parkinson’s disease cannot be eliminated completely but its symptoms can be reduced, damages can be repaired and its progression can be delayed considerably by using various simple and natural things. In this eBook, a natural program to treat Parkinson’s disease is provided online. it includes 12 easy steps to repair your body and reduce the symptoms of this disease.
The Role of Neurotrophic Factors in Parkinson’s Disease
Neurotrophic factors (NTs) play a significant role in the survival, growth, and maintenance of neurons in the brain, particularly in the context of Parkinson’s disease (PD). Key NTs like Brain-Derived Neurotrophic Factor (BDNF), Nerve Growth Factor (NGF), and Glial cell line-Derived Neurotrophic Factor (GDNF) have shown potential in protecting dopaminergic neurons, which are crucially affected in PD.
BDNF is particularly important for the survival of neurons within the brain’s dopaminergic pathways. Animal models have demonstrated that increasing BDNF levels, either through physical activity or gene therapy, can provide neuroprotective benefits, improving motor function and potentially slowing disease progression. However, clinical trials using BDNF directly or through gene therapies have met with limited success due to challenges such as delivery methods, immune responses, and insufficient diffusion in the brain tissues
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Similarly, GDNF, another neurotrophic factor, has been extensively studied for its ability to protect and promote the regeneration of dopaminergic neurons. While preclinical studies have shown promising results, clinical applications have faced hurdles such as complications with delivery systems and a lack of sustained therapeutic effects in humans
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Current research is focused on optimizing ways to increase the efficacy and delivery of these neurotrophic factors, including new delivery techniques and formulations that could overcome previous limitations. While these treatments are still largely experimental, they offer hope for future PD therapies by targeting the root cause of neuronal degeneration rather than just alleviating symptoms
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The Parkinson’s Protocol™ By Jodi Knapp Parkinson’s disease cannot be eliminated completely but its symptoms can be reduced, damages can be repaired and its progression can be delayed considerably by using various simple and natural things. In this eBook, a natural program to treat Parkinson’s disease is provided online. it includes 12 easy steps to repair your body and reduce the symptoms of this disease.