Depression and Anxiety in Parkinson’s Disease

September 26, 2024

The Parkinson’s Protocol™ By Jodi Knapp Parkinson’s disease cannot be eliminated completely but its symptoms can be reduced, damages can be repaired and its progression can be delayed considerably by using various simple and natural things. In this eBook, a natural program to treat Parkinson’s disease is provided online. it includes 12 easy steps to repair your body and reduce the symptoms of this disease. 


Depression and Anxiety in Parkinson’s Disease

Depression and anxiety are common non-motor symptoms in Parkinson’s disease (PD) and can significantly affect a patient’s quality of life. These mood disorders often appear early in the disease, sometimes even before motor symptoms emerge.

Depression in Parkinson’s Disease:

  1. Prevalence: Depression affects approximately 40-50% of people with PD, ranging from mild symptoms to major depressive disorder.
  2. Causes: The exact cause is multifactorial, involving both the neurodegenerative changes in the brain and the psychological impact of living with a chronic illness. PD affects dopamine and serotonin levels, both of which are crucial for mood regulation.
  3. Symptoms:
    • Persistent sadness or low mood
    • Fatigue and loss of energy
    • Loss of interest in activities once enjoyed (anhedonia)
    • Changes in appetite or sleep patterns
    • Feelings of hopelessness or worthlessness
    • Suicidal thoughts in severe cases
  4. Treatment:
    • Antidepressants: Selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs) are commonly used.
    • Cognitive-behavioral therapy (CBT): Talk therapy can help address negative thoughts and behaviors.
    • Exercise: Physical activity has been shown to improve mood and reduce depressive symptoms in PD patients.

Anxiety in Parkinson’s Disease:

  1. Prevalence: Anxiety affects around 30-40% of PD patients, often coexisting with depression.
  2. Causes: Similar to depression, anxiety in PD may result from both neurochemical changes and the stress of coping with the disease. It can also be linked to medication “off” periods (when PD symptoms worsen as medication wears off).
  3. Symptoms:
    • Excessive worry or fear
    • Restlessness and irritability
    • Physical symptoms like increased heart rate, sweating, or shortness of breath
    • Panic attacks, which can occur unexpectedly
  4. Treatment:
    • Medications: SSRIs and benzodiazepines (with caution due to side effects) are often prescribed to alleviate anxiety.
    • Cognitive-behavioral therapy (CBT): This approach can help reduce anxious thoughts and improve coping mechanisms.
    • Mindfulness and relaxation techniques: Practices such as deep breathing, meditation, and yoga can help manage anxiety symptoms.

Impact on Quality of Life:

Both depression and anxiety in PD are associated with reduced quality of life, worsening motor symptoms, and increased disability. Addressing these issues is critical to comprehensive Parkinson’s care, as mood disorders can exacerbate physical symptoms and hinder treatment adherence.

Integrated Approach:

  • Regular mental health evaluations
  • Tailored treatment plans, including both pharmacological and non-pharmacological interventions
  • Support from caregivers and mental health professionals

By managing depression and anxiety, patients with Parkinson’s can improve their overall well-being and quality of life.


The Parkinson’s Protocol™ By Jodi Knapp Parkinson’s disease cannot be eliminated completely but its symptoms can be reduced, damages can be repaired and its progression can be delayed considerably by using various simple and natural things. In this eBook, a natural program to treat Parkinson’s disease is provided online. it includes 12 easy steps to repair your body and reduce the symptoms of this disease.