What is the main cause of Parkinson’s Disease?

March 8, 2024

The Parkinson’s Protocol™ By Jodi Knapp Parkinson’s disease cannot be eliminated completely but its symptoms can be reduced, damages can be repaired and its progression can be delayed considerably by using various simple and natural things. In this eBook, a natural program to treat Parkinson’s disease is provided online. it includes 12 easy steps to repair your body and reduce the symptoms of this disease. 


The exact cause of Parkinson’s Disease (PD) is not fully understood, but it is believed to involve a combination of genetic, environmental, and lifestyle factors. Several hypotheses have been proposed regarding the underlying mechanisms of PD, but no single cause has been identified. However, researchers have identified several key factors that may contribute to the development of Parkinson’s Disease:

  1. Genetics: While most cases of Parkinson’s Disease occur sporadically, a small percentage of cases (around 10-15%) are believed to have a genetic component. Certain genetic mutations and variations have been associated with an increased risk of developing PD. These genetic factors can influence various aspects of cellular function, including the regulation of protein aggregation, mitochondrial function, and neurotransmitter metabolism.
  2. Environmental Factors: Exposure to certain environmental toxins and chemicals has been implicated in the development of Parkinson’s Disease. For example, exposure to pesticides, herbicides, industrial chemicals, and heavy metals (such as manganese) has been associated with an increased risk of PD. Additionally, head injuries and trauma may also contribute to the development of Parkinson’s Disease.
  3. Alpha-Synuclein Aggregation: One of the hallmarks of Parkinson’s Disease is the accumulation of abnormal protein aggregates, particularly alpha-synuclein, within neurons. These aggregates, known as Lewy bodies, disrupt cellular function and contribute to neuronal damage and cell death. The mechanisms underlying alpha-synuclein aggregation and its role in PD pathogenesis are areas of active research.
  4. Mitochondrial Dysfunction: Mitochondria are cellular organelles responsible for producing energy and regulating cellular metabolism. Dysfunction in mitochondrial function and oxidative stress have been implicated in the pathogenesis of Parkinson’s Disease. Mitochondrial dysfunction can lead to energy deficits, impaired cellular homeostasis, and increased susceptibility to oxidative damage, contributing to neuronal degeneration.
  5. Neuroinflammation: Inflammation within the central nervous system (neuroinflammation) has been implicated in the progression of Parkinson’s Disease. Activated microglia, the immune cells of the brain, release pro-inflammatory cytokines and reactive oxygen species, contributing to neuronal damage and degeneration. Chronic neuroinflammation may exacerbate neurodegeneration and contribute to disease progression.

It’s important to note that Parkinson’s Disease is a complex disorder with multifactorial origins, and the interplay between genetic predisposition, environmental exposures, and other factors likely contributes to its development. Ongoing research is needed to further elucidate the underlying mechanisms of Parkinson’s Disease and identify potential targets for therapeutic intervention.


The Parkinson’s Protocol™ By Jodi Knapp Parkinson’s disease cannot be eliminated completely but its symptoms can be reduced, damages can be repaired and its progression can be delayed considerably by using various simple and natural things. In this eBook, a natural program to treat Parkinson’s disease is provided online. it includes 12 easy steps to repair your body and reduce the symptoms of this disease.